The results presented here provide limited support for the hypothesis that SOB modulates expression of genetic polymorphisms of the dopamine system. Thus they add to previously published studies that have documented SOB interactions with the expression of dopamine system genetic polymorphisms, including interactive effects on psychiatric disorders [46], [47] and BMI in women with seasonal affective disorder [5]. However, given the limited sample size as well as the factorial nature of our statistical models, and the possibility of type I error, the results must be considered tentative.
