We estimated the genetic correlations between different ancestries using Popcorn76, which can estimate both the genetic-effect correlation (ρge) as correlation coefficient of the per-allele SNP effect sizes and the genetic-impact correlation (ρgi) as the correlation coefficient of the ancestry-specific allele variance-normalized SNP effect sizes. Populations in 1000 Genomes were used as reference for their corresponding population. A large sample size and number of SNPs are required for accurate estimation, which explains the nonrobust estimates for EAS and SAS samples.
