We used DNA extracted from whole blood samples from individuals with biopsy confirmed FSGS and no family history of FSGS for these studies. These samples were collected as part of our ongoing studies of the genetic basis of FSGS in accordance with a protocol approved by the Institutional Review Board at the Brigham and Women’s Hosptial. We performed genome-wide SNP genotyping using Illumina microarrays. We genotyped DNA from 56 African-Americans and 61 individuals of European descent, with FSGS. We excluded individuals with a strong family history of FSGS from this analysis. We used data from 1827 African American and 1641 European American individuals as a control dataset.
