2010a) and unaffected co-twins of schizophrenia patients (Hall et al., 2011b), the current findings suggest that abnormal early auditory gamma-band response may be a biomarker reflecting the clinical risk for the development of psychosis. However, we did not find abnormal gamma band responses to predict conversion to psychosis among CHR patients. While the lack of a converter vs. non-converter effect may indicate that abnormal gamma band responses reflect clinical vulnerability for psychosis, with other factors determining whether a psychotic disorder subsequently develops, larger sample sizes are needed to address this question definitively. Such large sample CHR studies are currently underway (e.g., Cannon et al., 2008).
