Figure 2, panel C, shows the mean DrInC negative consequences total scores by treatment condition for each of the follow-up points at which the measure was administered. Negative consequences declined over time in all treatments. A linear mixed model analysis was used to examine differences in DrInC Total Score as a function of treatment condition over the 27 months of follow-up. PDA at baseline (transformed) served as a covariate. Results indicated no main effect for Treatment [F (2, 789) = 1.50], a significant effect for Time [F (5, 789) = 75.12; p < .001], and no significant Treatment X Time interaction [F (10, 789) = 1.08]. Equivalent results were found when the same analyses were conducted on the individual DrInC subscales.