Patterns of association observed at age 14 were similar to patterns observed at 31 and very different for the two loci. For CHRNA3-rs1051730[A], at both time points, association was driven by the category including the heaviest smokers. In contrast, TTC12-rs10502172[G] is equally overrepresented in low- and high-quantity smokers than non-smokers at both time points (see Table 1).
