YLLs for each disorder were estimated by multiplying deaths occurring as a result of a given disorder, by the reference standard life expectancy at the age the death occurred. Standard life expectancy data came from GBD 2010 standard model life tables [12]. The number of deaths occurring as a result of each mental, neurological, and substance use disorder was estimated from cause of death data (by age, gender, year, region and country) available for 235 of 291 diseases and injuries in GBD 2010 [10]. These estimates were based on comprehensive searches of data sources such as vital registrations, verbal autopsies, and mortality surveillance databases, dating back to 1980, for 187 countries. Codes from different revisions of the ICD cause of death directory were matched to GBD 2010’s list of diseases and injuries. Deaths allocated to unclear or imprecise diagnoses (for example, deaths assigned to conditions that were not likely to be the underlying cause of death) were reassigned using standard algorithms [13]. Deaths and YLLs were estimated for schizophrenia, alcohol use disorders, drug use disorders, anorexia nervosa, epilepsy, Alzheimer’s disease,