Chunk #32 — Results — Power comparison — Three out of three traits associated with the QTL (Figure 2C)

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A comparison of multivariate genome-wide association methods.

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Again, MV-PLINK, MV-SNPTEST, MultiPhen and MV-BIMBAM performed similar and best under simulation scenarios with a negative genetic correlation; in this case, their power increased with increasing residual correlation. However, for scenarios with a positive genetic correlation, power of MV-PLINK, MV-SNPTEST, MultiPhen and MV-BIMBAM increased with decreasing residual correlation.