In addition to reduced DMN connectivity, increased intrinsic connectivity has been reported by several resting-state fMRI studies between frontal-parietal regions.59,61,63 The basis for these connectivity increases remains unclear; although some authors suggest that they represent compensatory mechanisms,59,61,63 there is as yet no evidence that such changes improve cognition. An alternative explanation is that damage to one network enhances connectivity within regions that normally feature an anti-correlated relationship with the damaged network.58
