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Chunk #10 — Results — The Polygenic Index Repository

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Resource profile and user guide of the Polygenic Index Repository.
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the y-axis scale is different. The bottom panel of Figure 3 shows the difference between the R2 of the single-trait Repository PGI and that of a PGI we constructed using the largest non-overlapping GWAS whose summary statistics are in the public domain. The Repository PGIs are almost always at least as predictive as the PGIs based on publicly available GWAS results. For the corresponding results for the multi-trait PGIs, see Supplementary Figure 1. The multi-trait PGIs are usually at least as predictive as the single-trait PGIs (Supplementary Figure 1C and Supplementary Table 3).