cannot be fulfilled in a number of chromosomal regions or in a number of genes in which the density of SNPs is too low to meet this stringent requirement (see Supplement of [14] for list of the genes that cannot be assessed with these criteria using the Affymetrix platform). There are only about ¼ million autosomal SNPs that are shared between the ca. 900 K and 1 M autosomal SNPs evaluated by the Affymetrix and Illumina platforms, respectively, further exacerbating this problem in many genomic regions.