age, though Bcl2 or TRAF2DN single transgenics had a regular lifespan. As in the case of the TCL1 transgenic mice, malignant cells were B220+CD5+, with a small number of animals having B-cell expansions of a different subtype. In conclusion, it is still uncertain if the TRAF2DN/BCL2-driven leukemia resembles an indolent or an aggressive form of CLL [21].
