For LD Hub, we list a few suggestions/limitations here: In order for estimates of the genetic correlation to be reliable we suggest that traits uploaded meet the following criteriaHeritability (H2) Z score is at least > 1.5 (optimal > 4)Mean Chi square of the test statistics > 1.02The intercept estimated from the SNP heritability analysis is between 0.9 and 1.1As we aim to provide an analysis pipeline that is as systematic as possible, we used a very inclusive strategy for data selection, where we expect a small proportion of the analyses (especially for the traits with notes in Table S1) to return null results.LD Hub is currently designed for GWAS studies involving European populations exclusively. As the number of publicly available GWAS involving other ethnicities increases we will extend LD Hub to include these.
