The Research Electronic Data Capture (REDCap) data management platform is an example of a CTSA-funded clinical research software application that has grown beyond its single institutional use case to be shared with institutions across the world [26]. Since its initial development at Vanderbilt University, REDCap has been adopted by more than 3,207 partners in 128 countries as of mid-December 2018 (Figures 1 and 2, Table 1). REDCap is a secure web application for building and managing online surveys and databases, designed to support data capture for research studies [26]. The diverse applications of REDCap (Figure 3) include support of basic science research studies [27,28], data collection for clinical trials [29,30], registries and cohort studies [31–35], quality reviews for clinical practice [36–39], comparative effectiveness trials [40–42], patient questionnaires [43–45], clinical decision support applications [46], and operational support [47]. REDCap has limited personnel requirements (one support person can easily manage hundreds of projects [48]) but does require typical web infrastructure including one or more secure web servers running PHP, MySQL/MariaDB, and SMTP email services.
