Chunk #35 — Discussion

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Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.

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Beyond OPRM1, we also observed a GWS association with OA for the intergenic variant rs13333582. The observations that variants in high LD with rs13333582 had much weaker associations and that rs13333582 is located in a repetitive sequence both suggest the association with OA was a false positive.