Additional analyses were conducted using the samples of the patients who underwent major abdominal surgery, patients with METH dependence/psychosis, patients with alcohol dependence, patients with eating disorders, healthy volunteers with personality profile data and post-mortem specimens for the expression analysis. For all of the genotype data used in these analyses, the distributions were checked using the χ2 test, and the absence of significant deviation from the theoretical distribution expected from Hardy–Weinberg equilibrium was confirmed (Supplementary Table 13).
