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Chunk #80 — Methods — Power Calculations

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A genome-wide investigation of SNPs and CNVs in schizophrenia.
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by 10,000. Solutions to θ based on fixed values of the other parameters were found by an iterative root-finding procedure (function “uniroot” in the R statistical package, http://www.r-project.org/). The Total Lambda-s expected based on k independent SNPs each with a given OR and MAF was found using equations in Camp et al. [61].