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Chunk #12 — Materials and methods — Analytic Methods

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Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.
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Linkage disequilibrium (LD) and genotype quality were analyzed using Haploview (Barrett et al, 2005). This freely available software package allows for estimation of several LD statistics, including pairwise LD correlations, or r2. All SNPs were checked for Hardy Weinberg Equilibrium within ethnic groups using Haploview and further verified in SPSS version 15.0.