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Chunk #68 — Methods — Gene-based association analyses

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Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
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We performed gene-based association analysis for PAU or AUD in multiple ancestries using MAGMA implemented in FUMA78. Default settings were applied. Bonferroni corrections for the number of genes tested (range from 18,390 to 19,002 in different ancestries) were used to determine GWS genes.