Chunk #30 — Materials and Methods — Anthropometric measurements

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A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

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For ARIC HyperGEN, GenNet and WHI, BMI was calculated from height and weight measured at time of study enrollment. In MEC, self-reported height and weight were used to calculate baseline BMI. A validation study within MEC has shown high validity of self-reported height and weight. Specifically this study showed that BMI was under-estimated based on self-reported compared to measured weight, but the difference was small (<1 BMI unit) and comparable to the findings from national surveys [45].