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Chunk #51 — Discussion

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Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning.
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The age-related differences obtained in the late paired condition could also be influenced by the fact that, after 2.0 g/kg, adults exhibited lower blood and brain ethanol levels at 32.5 min post-intubation than did adolescents. Nevertheless, BECs/BrECs in paired adults given 2.0 g/kg were still within the range that exerted appetitive effects in the younger animals. Finally, it could also be that adults show specific sensitivity to the motivational properties of ethanol in the SOC preparation at a dosage not tested in the present work.