PET data were examined for homogeneity of variance and analyzed using general linear models (GLM, Statistica 6.0, StatSoft, Tulsa, OK). For the %ΔBP, a repeated measures analysis of covariance (ANCOVA) was performed, with genotype and testing sequence as between subjects variables, region of interest as the within subjects variable, and drinking frequency (measured by the Lifetime Drinking History questionnaire 30) as the covariate. Subjective responses to alcohol were analyzed using repeated measures ANOVA with genotype and testing sequence as between subjects variables and time point as the within subjects variable. Post hoc comparisons were conducted using Newman-Kuel tests. Effect sizes were calculated using partial eta2 from Statistica, and Cohen’s f calculated using GPower 3.1.0 (Franz Faul, Universität Kiel, Germany).
