When a mixture of relatives from the same pedigree is included, one can use the averaged correlation coefficient discussed in the Method section. For example, with two siblings and one aunt/uncle, the averaged correlation coefficient r̄ = (1/3)0.5 + (2/3)0.25 = 1/3. The ESS for the two-sib-one-uncle is 1.8, larger than the value of 1.6 for three siblings.