Asian and Native American ancestry. Individuals who self-identify as Latino or Hispanic (LA) in the United States may have predominately European ancestry and may have relatively recent admixture with Native American ancestry or both Native American and African ancestry. In this report we focused on LA individuals with two-way admixture; cutoffs used were ⩾85% for the combination of European and Native American ancestry, <10% African ancestry and <3% Asian Ancestry. With exception of the South African data (see below), individuals not falling into the EA, AA and LA categories were excluded from analysis (on the basis of low case and/or control numbers).
