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Chunk #23 — Results — Gene Enrichment Analysis

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Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
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are the sizes of the ontologies after being matched against the gene coverage of population-specific GWAS data, along with the top empirical P-values observed for the various EA and AA gene lists, respectively): Maf transcription factors (n = 6 genes; P-values = 0.024 and 0.008); homeotic (Hox) AbdB genes (n = 16 genes; P = 0.026 and 0.008); chloride transport (n = 62 and 66 genes; P = 0.002 and 0.006); and glycine and serine metabolism (n = 27 and 33 genes; P = 0.001 and 0.014).