For the 2,636 samples with detectable SCNAs, ABSOLUTE provided purity and ploidy calls for 92% of cases, and designated the remaining samples as “polygenomic” (genomically heterogeneous) (Fig. 3a), (Online Methods; Supplementary Fig. 5). The fraction of called samples varied by disease type, from 34.6% (myeloproliferative disease; mostly non-aberrant genomes) to 96.7% (ovarian carcinoma, 100% aberrant genomes), with a median call-rate of 79.2% (Fig. 3a).
