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Chunk #23 — APPRIS ANNOTATIONS

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APPRIS: annotation of principal and alternative splice isoforms.
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More than 8175 of the annotated transcripts would lose at least one trans-membrane helix and 543 would have lost a signal sequence. Almost 50 000 alternative splice variants (49 899, 94.5% of variants tagged as alternative) were less conserved across related species than the principal variant (from the results of CORSAIR, CExonic or INERTIA).