of alcohol (slurred speech, stumbling, etc.) when they first began drinking. In a pilot study of college freshmen, individuals who reported a low level of response to alcohol and who were assigned to a prevention program structured around how a low physiological response affects heavy drinking, showed greater decreases in alcohol use as compared to individuals with a low level of response who were assigned to a standard prevention program that covered the same information, but not in the context of a low level of response framework. Individuals who did not have a low level of response to alcohol did better in the standard prevention program (Schuckit et al., 2012). We assessed level of response in the Spit for Science survey and used these data to invite a subset of students to participate in an intervention study designed to replicate the Schuckit et al. (2012) finding. We too found modest support for individuals with a low level of response showing decreased alcohol use in the level of response prevention program compared to the non-tailored program, particularly for high risk drinking practices such as maximum number of drinks in a day (Savage et al., unpublished). Interestingly, we found that the individuals
