In conclusion, our findings underscore the great potential to utilize the brain oscillations evoked under cognitive conditions as phenotypes in combination with neurochemical and neuroanatomical information in deciphering the interaction of the subsystems involved in the pathophysiology of complex neuropsychiatric diseases. We expect that the identification of genes that regulate cognitive processes will be of enormous benefit to the field of psychiatric genetics. These data support the notion that carefully chosen brain oscillations may be adopted as endophenotypes. Nevertheless, further studies using an independent data sample are warranted, and as with all genetic studies of complex phenotypes, caution must be advised until the findings are replicated.