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Chunk #20 — Discussion

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Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
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fracture risk. On the other hand, when no correlation is observed between gene expression and a particular SNP, it is difficult to draw conclusions. A correlation might be missed if the expression of the transcript was not measured in a relevant tissue or if the expression of a particular splice-variant was not measured.27