Total genomic DNA/RNA was extracted from all cells using AllPrep DNA/RNA/Protein kit (Qiagen) according to the manufacturer's instructions. Gene expression analysis was performed at the Institute for Molecular Medicine Finland (FIMM) Technology Center, University of Helsinki, using Illumina Human-12 v4 Expression BeadChips. For further analyses, data were processed by removal of background and quantile normalization. The data analysis was performed with R statistics and Chipster (Kallio et al., 2011). All iPSC lines analyzed were between passages (p) 9 and 17. Genes were filtered on the basis of their SD (2 SDs = 95%).
