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Chunk #22 — Results — Integration with functional genomic data

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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
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We next performed gene-set analyses to understand implicated genes in the context of pathways and found four significant, Bonferroni-corrected gene sets (Supplementary Data 2). Of note, the two gene sets identified in the EUA data point towards a role for the immune system in PTSD. This is supported by a number of TNF-related genes summarized in a significant gene-set in AFA.