As the world's population continues to grow, so does the demand for crops with particular characteristics such as drought resistance, high yield and resistance to pests and pathogens. The cultivation and repeat harvesting of wild “landrace” wheat varieties has led over time to the emergence of domesticated “elite” wheat varieties with desirable phenotypic characteristics. In an attempt to elucidate some of the important genetic variants responsible for these characteristics, we collected single nucleotide variants (SNVs) from four elite UK bread wheat varieties (Avalon, Cadenza, Rialto, and Savannah) and have predicted the functional effects of these mutations when compared to four landrace wheat varieties from the Watkins collection held at the John Innes Centre, Norwich, UK (304, 306, 311, and 328). For this analysis, SNVs were mapped onto the draft wheat genome assembly and six-frame translated. For each reading frame, SUPERFAMILY [Gough et al., 2001] and Pfam [Sonnhammer et al., 1997] domain assignments on the full-length amino acid sequence were made and the corresponding AASs were evaluated using our unweighted method. We found several biologically interesting SNV differences between the landrace