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Chunk #11 — Results — Simulations with Simulated Genotypes

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Leveraging population admixture to characterize the heritability of complex traits.
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The results also demonstrate the relationship between hγ2 and the parameters FSTC, θ, and h2. For a fixed value of r, phenotypes with a larger h2 will have larger genetic effects resulting in larger hγ2. When ancestral populations are genetically distant (larger FSTC), variants are more likely to have a different frequency in the ancestral populations resulting in a concomitant increase in hγ2. Increasing the variance of θ results in a larger standard error around the heritability estimates.