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Chunk #43 — Results — The effect of inbreeding on personality traits

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Maintenance of genetic variation in human personality: testing evolutionary models by estimating heritability due to common causal variants and investigating the effect of distant inbreeding.
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Overall, these results provide strong evidence that inbreeding affects some personality traits, consistent with being influenced by a load of mutations that tend to be rare, recessive, and deleterious, as predicted under mutation-selection balance. These inbreeding effects are not consistent with selective neutrality or balancing selection models for highly polygenic traits, as these provide no reason to expect bias in the direction of dominance across many loci.