Chunk #96 — Fyn

Source

Protein kinases and addiction.

Embedded

yes

Text

Fyn plays an important role in synaptic plasticity and LTP. Knockout of the fyn gene, and not other members of Src kinase family, results in abnormal hippocampal development, deficient hippocampal LTP, and impaired spatial learning.260 Reintroduction of Fyn into knockout mice rescues hippocampal development and induction of LTP.260