Addition of sarcosine – a natural, widespread amino acid – is currently considered as a beneficial and safe augmentation method of neuroleptic treatment in schizophrenia. In the available literature, significant improvement in both negative symptoms subscale and total symptomatology scores in the Positive and Negative Syndrome Scale after sarcosine use was described.14,15 In these projects, patients received a dose of 2 g of sarcosine per day.
