In this study, as noted earlier, for the children with the most extreme trauma exposure, it was MAOA-H that was associated with inattention. More than 70% of the children in this group met criteria for PTSD, with diagnoses of depression also overrepresented in children with the most severe trauma histories. MAOA-H has been associated with MDD in some (39,40), but not all (41), studies. If the inattention associated with low to moderate histories of trauma exposure is associated with a different diagnostic profile than inattention associated with more extreme histories of trauma exposure, one might not expect the same genes to confer risk for inattention in both groups.
