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Chunk #30 — Discussion

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Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: possible differential markers of affective and impulsive pathways of risk for alcohol use disorder.
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Our study is, of course, not without limitations. First and foremost, while AUDIT scores represented in our sample spanned a wide range (0–23), the majority of our participants scored below 8 – the generally accepted threshold for clinical significance. However, a substantial minority of participants scored 8 or above (n=197, 26%), suggesting our findings are not restricted to individuals who are merely social drinkers. Even more tellingly, we confirmed the potential clinical relevance of our model in analyses predicting clinical diagnosis of an AUD.