(GCRC) in order to ensure that participants were in good physical health and were medically eligible to take the study medication and to participate in the alcohol challenge. Of the total of 124 participants (39 women) who were screened in the laboratory, 53 completed the physical exam, 7 of whom were ineligible due to a medical reason and 6 of whom decided not to participate in the trial. These procedures resulted in a total of 40 completers.