It is likely that psychiatric genetic research will increase exponentially in future decades, as more sophisticated molecular research techniques are used to discover the underlying pathways to common mental illnesses, such as major depression (Appelbaum, 2004). Engaging potential research participants of underrepresented groups in meaningful discourse about their concerns as research subjects is essential in eliciting their trust and collaboration. This effort represents a preliminary step towards ensuring that benefits derived from genetic research are proportionally realized across various racial and ethnic groups. Additional research with larger, more representative samples is necessary to systematically investigate the specific ways in which attitudes predict willingness and actual participation in genetic studies of psychiatric disorders.