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Chunk #13 — Results — Subject characteristics

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A GABRA2 polymorphism improves a model for prediction of drinking initiation.
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Table 1 provides the descriptive statistics of the nine variables of interest in the final sample of 674. Most subjects (86%) were members of high-risk AD families. About 40% of subjects endorsed one or more CD symptoms. Slightly less than 20% of the sample endorsed MBFD. The average interview age was approximately 15.5 years; interview age was evenly distributed across the 4-year age range of subjects. Using only one subject per family, the T allele was absent in 14% of subjects, 48% had a single T allele, and 38% had two T alleles. The frequency of the T allele was not different between control and high-risk families (p = 0.91); this was true for both AE and AA control and high-risk families (p = 0.78 and p = 0.62, respectively). A first drink was reported by slightly over 40% of subjects; on average, subjects who drank did so 2.0 ± 1.7 years prior to being assessed.