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Chunk #2 — INTRODUCTION

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KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns.
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PredPh2ospho (11) predicts phosphorylation sites limited to four protein major kinase families, such as CDK, CK2, PKA and PKC, and four protein kinase groups (AGC, CAMK, CMGC and TK) with predictive accuracy 83–95 and 76–91%, respectively. GPS (12,13), is a group-based phosphorylation site predicting and scoring platform which clustered the 216 unique protein kinases in 71 groups. PPSP (4) developed an approach based on Bayesian decision theory for predicting the potential phosphorylation sites accurately for around 70 protein kinase groups.