The biological bases of major psychiatric disorders have been studied for decades, yet they remain largely unresolved. Evidence from both clinical and biomedical literature has demonstrated that individuals with these conditions show differences in circulating immunologic markers, functional capacities of isolated immune cells, and atypical prevalence of clinical immune-related phenotypes compared to individuals not affected by psychiatric or neurodevelopmental disorders (Eaton et al. 2006; Fineberg & Ellman 2013; Gesundheit et al. 2013; Gibney & Drexhage 2013; Jones & Thomsen 2013; Dowlati et al. 2010; Masi et al. 2015; Modabbernia et al. 2013; Rege & Hodgkinson 2013; Hess et al. 2016). It remains unclear what roles (if any) altered immunologic functions may play in the major psychiatric phenotypes, though plausible mechanisms linking altered immune functions with neurobiological changes during early brain development and in fully developed adults have been identified (Deverman & Patterson 2009; Felger & Lotrich 2013; Meyer 2014; Miller et al. 2013; Oskvig et al. 2012; Sekar et al. 2016; Shatz 2009; Smith et al. 2007). While some studies have already suggested potential genetic bases for the immune dysregulation
