structural MRI study on the same groups of subjects, we found that the AUD group showed lower volumes in prefrontal cortex and left hippocampus, which were associated with poorer visuospatial memory performance [54]. Furthermore, in another study on the same sample, we found that AUD subjects manifested hyperconnectivity across the parahippocampal hub regions [63], adding support to the current finding related to memory deficits. On the other hand, it is surprising that none of the scores related to executive functioning in the TOLT were significantly different from controls, possibly suggesting a partial or complete recovery of these functions in the AUD group due to abstinence. It is also possible that the current study failed to capture deficits in additional domains, as the data involved in the current study were limited to only two tests and the sample size was only modest. Future studies may employ a comprehensive and sensitive battery of neuropsychological tests in a larger sample of abstinent AUD individuals, to map neuropsychological performance in multiple domains.
