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Chunk #18 — RESULTS — Array-based replication analysis

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Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.
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both family-based samples, three CNVRs presented at least nominally significant CNVR-adjusted one-sided P-values (≤0.025; Table 2). None of these CNVR associations remained significant after strict Bonferroni correction, which may potentially be due to an insufficient sample size. Among the three CNVRs with nominally significant CNVR-adjusted P-values, again those two CNVRs tagged by SNPs were found. Additional support was given for CNVR 4q32.1, which does not comprise any gene.