This study combines individual genotype data published in 2011 by the PGC Bipolar Disorder and the Schizophrenia Working Groups. Description of the sample ascertainment can be found in the respective publications (17, 18). In addition, four bipolar datasets not included in the primary meta-analysis (although used for the replication phase) are now included: three previously not published bipolar datasets including additional samples from Thematically Organized Psychoses (401 cases, 171 controls), French (451 cases, 1,631 controls), FaST STEP2/TGEN (1,860 cases) and one published dataset Sweden (824 cases, 2,084 controls) (19). The unpublished samples are further described as supplementary information in the original PGC BP study (14). FaST STEP2/TGEN BP cases were combined with GAIN/BIGS BP cases and controls from MIGen (20) to form a single sample (Supplementary Table 2). In the PGC analyses, genotype data from control samples were used in both SCZ and BP GWAS studies.
