paperKB
coga / coga-kb
Help
Sign in

Chunk #42 — Results — Optimization, validation, and accuracy estimation of the reference panel and digital deconvolution method

Source
Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.
Embedded
yes

Text

Once we identified the optimal approach to perform digital deconvolution from brain RNA-seq, we benchmarked it by using three sets of independent pure cell populations and simulated chimeric libraries.