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Chunk #7 — MEA technology — Device types and terminology

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Revealing neuronal function through microelectrode array recordings.
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Over the years, a wide repertoire of terms has been used to refer to and distinguish between all the different forms of MEAs, e.g., emphasizing the type of transducers used (multi-transistor array, microelectrode array, multielectrode array, micro-nail array, capacitive-coupled array, 3D MEA), the type of substrate (active array, passive array, silicon array, CMOS array), the shape of the device (needle-type probe, polytrode, neuro dish), the channel count (multichannel array), the electrode density (HDMEA) or the application (implantable array, in vivo MEA, in vitro MEA) and more. We would therefore like to briefly explain the terminology used in the context of this review. We generalize the term microelectrodes and MEA to cover both substrate-integrated planar MEAs and implantable neural probes. We also include capacitive-coupled devices, such as multi-transistor arrays in the definition of MEAs. We then distinguish between implantable, in vivo MEAs, such as polytrodes and neural probes, and in vitro MEAs that generally include a cell culture dish or some other sort of medium chamber. Further, we classify the different array architectures, as will be explained in Section Advances in