Both sets of association results underwent the same set of quality-control filters as the autosomal analyses prior to meta-analysis. Additionally, we dropped a small number of SNPs with male-female allele frequency differences above 0.005 in UKB. The meta-analysis was conducted in METAL35, using sample-size weighting. Only SNPs that were present in both cohorts’ results files were used. To adjust the test statistics for bias, we inflated the standard errors using the LD Score regression intercept estimated from our main autosomal analysis (1.113).
